Pentadecapeptide BPC 157 accelerates tendon-to-bone healing in rats
Primary theme: Tissue repair
Rodent model showed accelerated tendon-to-bone healing markers with stable gastric pentadecapeptide administration.
J. Orthop. Res. · 2018Source
Library
Peptide Research Studies
A curated index of peptide studies — from foundational pharmacology to recent preclinical work. Search by compound name, study topic, or use-case keyword like recovery, anxiety, or growth hormone.
32 studies
Thymosin β4 promotes cardiomyocyte survival in ischemic injury models
Primary theme: Cardiac regeneration
Investigation of Tβ4's role in epicardial activation and vascular regeneration following induced ischemia.
Nature · 2014Source
Thymosin β4 and skeletal muscle repair
Primary theme: Muscle recovery
Tβ4 supports actin sequestration, cell migration, and angiogenesis associated with skeletal muscle repair in rodent models.
Ann. N.Y. Acad. Sci. · 2012Source
Semax modulates BDNF and trkB expression in rat hippocampus
Primary theme: Cognition
Intranasal Semax administration produced rapid changes in neurotrophin gene expression linked to cognition.
Neurosci. Lett. · 2008Source
Anxiolytic activity of Selank in rodent models
Primary theme: Anxiolysis
Selank demonstrated anxiolytic effects comparable to benzodiazepines without sedative profile in elevated plus-maze tests.
Bull. Exp. Biol. Med. · 2011Source
Ipamorelin, the first selective growth hormone secretagogue
Primary theme: GH-axis pharmacology
Characterization of ipamorelin as a pentapeptide GHRP with minimal effects on cortisol and prolactin in vitro.
Eur. J. Endocrinol. · 1998Source
Sustained GH and IGF-I response to CJC-1295 in healthy adults
Primary theme: GH-axis pharmacokinetics
DAC-modified GHRH analog produced sustained increases in GH and IGF-I in clinical pharmacokinetic study.
J. Clin. Endocrinol. Metab. · 2006Source
GHK-Cu in skin remodeling and wound repair
Primary theme: Skin & wound repair
Review of copper-tripeptide effects on collagen synthesis, antioxidant signaling, and fibroblast activity.
Cosmetics · 2015Source
Epitalon peptide induces telomerase activity in human somatic cells
Primary theme: Cellular senescence
Tetrapeptide induced telomerase activity and telomere elongation in cultured human fibroblasts.
Bull. Exp. Biol. Med. · 2003Source
Tesamorelin reduces visceral adipose tissue in HIV-associated lipodystrophy
Primary theme: Metabolic / body composition
GHRH analog demonstrated significant VAT reduction over 26 weeks in placebo-controlled trial.
N. Engl. J. Med. · 2010Source
Bremelanotide for hypoactive sexual desire disorder
Primary theme: Sexual function
Melanocortin receptor agonist evaluated in two phase-3 trials for premenopausal HSDD.
Obstet. Gynecol. · 2019Source
MOTS-c regulates metabolic homeostasis and exercise capacity
Primary theme: Metabolic regulation
Mitochondrial-derived peptide shown to influence insulin sensitivity and AMPK signaling in murine models.
Cell Metab. · 2015Source
Small-molecule NNMT inhibitor in diet-induced obesity models
Primary theme: Adiposity / metabolism
Selective NNMT inhibitor reduced adipose tissue mass and improved metabolic markers in obese mice.
Biochem. Pharmacol. · 2018Source
Delta sleep-inducing peptide and slow-wave sleep modulation
Primary theme: Sleep architecture
Early investigations of DSIP's role in sleep architecture and stress-axis regulation.
Eur. Neurol. · 1984Source
Cardioprotective effects of hexarelin in experimental models
Primary theme: Cardioprotection
GHRP-class peptide demonstrated GH-independent cardioprotection in ischemia-reperfusion models.
Endocrine · 2003Source
BPC 157 and the brain-gut axis in stress models
Primary theme: Gut health & stress
Review of pentadecapeptide effects on gut mucosa integrity and stress-induced lesions in rodents.
Curr. Neuropharmacol. · 2019Source
Semax in experimental cerebral ischemia
Primary theme: Neuroprotection
Neuroprotective effects of Semax demonstrated in rodent middle cerebral artery occlusion models.
Bull. Exp. Biol. Med. · 2010Source
Long-R3-IGF-I biological activity and extended half-life
Primary theme: Anabolic signaling
Modified IGF-1 analog with reduced IGFBP affinity shows prolonged systemic activity in growth and protein-synthesis assays.
J. Endocrinol. · 1992Source
AOD-9604 / hGH fragment 176-191 and adipose tissue lipolysis
Primary theme: Lipolysis
C-terminal hGH fragment investigated for lipolytic activity independent of classical GH receptor effects.
Endocrinology · 2007Source
GHRP-2 stimulates pulsatile GH secretion in healthy adults
Primary theme: GH-axis pharmacology
GHRP-2 produced robust dose-dependent GH release in clinical pharmacology studies.
J. Clin. Endocrinol. Metab. · 1997Source
GHRP-6, ghrelin receptor agonism and appetite signaling
Primary theme: GH-axis & appetite
Ghrelin receptor agonist with characteristic appetite-stimulating signature alongside GH release.
Endocrine · 2005Source
Kisspeptin-10 stimulates LH secretion in healthy men
Primary theme: Reproductive endocrinology
Single-bolus Kp-10 produced rapid increases in LH and testosterone via hypothalamic GnRH neurons.
J. Clin. Endocrinol. Metab. · 2011Source
Thymosin α1 as an immune modulator
Primary theme: Immune modulation
Review of Tα1 effects on T-cell maturation and cytokine signaling in chronic infection and immunosuppression models.
Ann. N.Y. Acad. Sci. · 2013Source
Intranasal oxytocin and social cognition
Primary theme: Social behavior
Meta-analytic evidence for oxytocin effects on trust, emotion recognition, and prosocial behavior.
Psychoneuroendocrinology · 2011Source
Adipotide induces white adipose tissue regression in obese primates
Primary theme: Adipose ablation
Proapoptotic peptidomimetic targeting prohibitin in adipose vasculature produced weight loss in nonhuman primates.
Sci. Transl. Med. · 2011Source
NAD+ metabolism in aging and metabolic disease
Primary theme: Cellular energetics
Review of NAD+ decline with age and effects of NAD-boosting interventions on mitochondrial function.
Cell Metab. · 2018Source
Cagrilintide and weight management in phase-2 trials
Primary theme: Weight management
Long-acting amylin analog showed dose-dependent weight reduction as monotherapy in overweight adults.
Lancet · 2021Source
Retatrutide triple-agonist phase-2 weight loss results
Primary theme: Weight management
GIP/GLP-1/glucagon triple agonist demonstrated up to ~24% body weight reduction at 48 weeks.
N. Engl. J. Med. · 2023Source
Tirzepatide for chronic weight management (SURMOUNT-1)
Primary theme: Weight management
GIP/GLP-1 co-agonist produced substantial weight loss and improved metabolic markers in 72-week trial.
N. Engl. J. Med. · 2022Source
Semaglutide once-weekly for weight management (STEP-1)
Primary theme: Weight management
GLP-1 analog produced ~15% mean body weight reduction in 68-week placebo-controlled trial.
N. Engl. J. Med. · 2021Source
Follistatin overexpression and myostatin inhibition in muscle growth
Primary theme: Anabolic / muscle growth
Gene-delivery follistatin increased muscle mass via myostatin pathway inhibition in murine models.
Mol. Ther. · 2009Source
hCG in restoration of testicular function on TRT
Primary theme: HPTA support
Review of hCG dosing strategies for preservation of intratesticular testosterone and fertility during exogenous androgen use.
Asian J. Androl. · 2013Source